International Chemical Safety Cards PARAQUAT ICSC: 0005 PARAQUAT 1,1'-Dimethyl-4,4'-bipyridinium dichloride (paraquat dichloride) Methyl viologen dichloride CH3(C5H4N)2CH3Cl2 Molecular mass: 257.2 CAS # 1910-42-5 RTECS # DW2275000 ICSC # 0005 UN # 2781 EC # 613-006-00-9 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO contact with oxidizing agents. In case of fire in the surroundings: powder, water spray, foam, carbon dioxide. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST! STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR! INHALATION Cough. Laboured breathing. Sore throat. Local exhaust or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration if indicated. Refer for medical attention. SKIN MAY BE ABSORBED! Redness. Skin burns. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention. EYES Redness. Pain. Face shield or eye protection in combination with breathing protection if powder. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Abdominal pain. Diarrhoea. Laboured breathing. Sore throat. Vomiting. Do not eat, drink, or smoke during work. Rinse mouth. Give plenty of water or bentonite clay in water, or give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Consult an expert! Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Sweep spilled substance into dry, sealable containers. Carefully collect remainder, then remove to safe place (extra personal protection: P3 filter respirator for toxic particles). Keep locked up. Separated from strong oxidants, strong bases, food and feedstuffs. Dry. Keep in the dark. Unbreakable packaging; put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs. T symbol R: 26/27/28 S: 1-13-45 UN Hazard Class: 6.1 UN Packing Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 0005 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

International Chemical Safety Cards PARAQUAT ICSC: 0005 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS, HYGROSCOPIC CRYSTALS. WATER SOLUTION OF PARAQUAT DICHLORIDE IS DARK RED. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating above 300°C and under influence of UV light producing toxic and corrosive fumes including nitrogen oxides, hydrogen chloride. Reacts with strong oxidants. Reacts with bases (hydrolysis). Unformulated products are corrosive to common metals. Inactivated by inert clays and by anionic surfactants. OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV: ppm; 0.1 (respirable fraction), 0.5 (total dust) mg/m3 (ACGIH 1991-1992). MAK: 0.1 ppm; mg/m3; (1992). OSHA PEL: TWA 0.5 mg/m3 (resp) skin NIOSH REL: TWA 0.1 mg/m3 (resp) skin NIOSH IDLH: 1 mg/m3 ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying and when dispersed. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes, the skin and the respiratory tract. Inhalation of this substance may cause lung oedema (see Notes). Ingestion can also cause lung hemorrhage and fibrosis. The substance may cause effects on the lungs, kidneys, liver, cardio vascular system and gastro intestinal tract , resulting in impaired functions, tissue lesions. Exposure to high concentrations may result in death. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact with skin may cause dermatitis, abnormalities and loss of fingernails. Lungs may be affected by repeated or prolonged exposure to the aerosol. PHYSICAL PROPERTIES Melting point (decomposes): 300°C Relative density (water = 1): 1.25 Solubility in water, g/100 ml at 20°C: 70 Vapour pressure, Pa at 20°C: <10 Relative vapour density (air = 1): 6.4-8.9 ENVIRONMENTAL DATA N O T E S Paraquat is an ion, (CH3(C5H4N)2CH3)++, CAS No. 4685-14-7. A dimethyl sulfate salt, a yellow solid, CAS No. 2074-51-2, has also been commercialized. Surfactants present in preparation may increase eye damage in humans. Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. The symptoms of lung fibrosis do not become manifest until several days. Do NOT take working clothes home. Gramoxone, Dextrone X, Esgram; and for various mixtures: Cleansweep, Weedol, Dexuron, TotaCol, Gramuron, Para-Col, Pathclear, Gramonol are trade names. ADDITIONAL INFORMATION ICSC: 0005 PARAQUAT © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.