International Chemical Safety Cards ARSENIC ICSC: 0013 ARSENIC Grey arsenic Metallic arsenic As Atomic mass: 74.9 CAS # 7440-38-2 RTECS # CG0525000 ICSC # 0013 UN # 1558 EC # 033-001-00-X TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. NO contact with strong oxidizers. NO contact with hot surfaces. Powder, water spray, foam, carbon dioxide. EXPLOSION Risk of fire and explosion is slight if in the form of fine powder or dust when exposed to hot surfaces or flames. Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting. EXPOSURE AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR! INHALATION Cough. Diarrhoea. Shortness of breath. Sore throat. Vomiting. Weakness. Grey skin. Closed system and ventilation. Fresh air, rest. Artificial respiration if indicated. Refer for medical attention. SKIN Redness. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. EYES Redness. or eye protection in combination with breathing protection if powder. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Diarrhoea. Nausea. Sore throat. Unconsciousness. Vomiting (further see Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Sweep spilled substance into sealable containers. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment (extra personal protection: complete protective clothing including self-contained breathing apparatus). Provision to contain effluent from fire extinguishing. Separated from strong oxidants, acids, halogens, food and feedstuffs. Well closed. Keep in a well-ventilated room. Do not transport with food and feedstuffs. T symbol R: 23/25 S: (1/2-)20/21-28-45 UN Hazard Class: 6.1 UN Packing Group: II Marine pollutant. SEE IMPORTANT INFORMATION ON BACK ICSC: 0013 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

International Chemical Safety Cards ARSENIC ICSC: 0013 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: ODOURLESS, BRITTLE, GREY, METALLIC-LOOKING CRYSTALS. PHYSICAL DANGERS: CHEMICAL DANGERS: Upon heating, toxic fumes are formed. Reacts violently with strong oxidants and halogens causing fire and explosion hazard. Reacts with nitric acid, hot sulfuric acid. Toxic arsine gas may be formed in contact with acid or acidic substances and certain metals, such as galvanized or light metals. OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV: ppm; 0.01 mg/m3 (as TWA) A1 (ACGIH 1994-1995). OSHA PEL: 1910.1018 TWA 0.010 mg/m3 NIOSH REL: Ca C 0.002 mg/m3 15-minute See Appendix A NIOSH IDLH: Potential occupational carcinogen 5 mg/m3 (as As) ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes, the skin and the respiratory tract. The substance may cause effects on the circulatory system, nervous system, kidneys and gastrointestinal tract , resulting in convulsions, kidney impairment, severe hemorrhage, losses of fluids, and electrolytes, shock and death. Exposure may result in death. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the mucous membranes, skin, kidneys, liver , resulting in neuropathy, pigmentation disorders, perforation of nasal septum and tissue lesions. This substance is carcinogenic to humans. PHYSICAL PROPERTIES Sublimation point: 613°C Relative density (water = 1): 5.7 Solubility in water: none ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment because it persists in the environment. N O T E S The substance is combustible but no flash point is available in literature. Depending on the degree of exposure, periodic medical examination is indicated. Do NOT take working clothes home. Refer also to cards for specific arsenic compounds, e.g., Arsenic pentoxide (ICSC # 0377), Arsenic trichloride (ICSC # 0221), Arsenic trioxide (ICSC # 0378), Arsine (ICSC # 0222). ADDITIONAL INFORMATION ICSC: 0013 ARSENIC © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.