International Chemical Safety Cards

CHLOROANILINE, p- ICSC: 0026

CHLOROANILINE, p-
Chloroaminobenzene, p-
4-Chloroaniline
C6H6ClN/ClC6H4NH2
Molecular mass: 127.6
CAS # 106-47-8
RTECS # BX0700000
ICSC # 0026
UN # 2018
EC # 612-010-00-8 (isomer mixture)
TYPES OF
HAZARD/
EXPOSURE 		ACUTE HAZARDS/
SYMPTOMS 		PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Water spray, powder, AFFF, foam, carbon dioxide.
EXPLOSION


EXPOSURE
PREVENT DISPERSION OF DUST! STRICT HYGIENE!
IN ALL CASES CONSULT A DOCTOR!
  • INHALATION
    		• Corrosive. Blue lips or finger nails. Blue skin. Dizziness. Headache. Laboured breathing.
    		Local exhaust or breathing protection.
    		Fresh air, rest. Refer for medical attention.
  • SKIN
    		• MAY BE ABSORBED! Redness (further see Inhalation).
    		Protective gloves. Protective clothing.
    		Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
  • EYES
    		• Redness. Pain.
    		Safety goggles, or eye protection in combination with breathing protection.
    		First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
  • INGESTION
    		• Nausea (further see Inhalation).
    		Do not eat, drink, or smoke during work.
    		Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention.
    SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
    Sweep spilled substance into sealable containers. Carefully collect remainder, then remove to safe place (extra personal protection: P3 filter respirator for toxic particles).
    		Separated from strong oxidants, food and feedstuffs.
    		Do not transport with food and feedstuffs.
    T symbol
    R: 23/24/25-33
    S: 28-36/37-45
    UN Hazard Class: 6.1
    UN Packing Group: II
    SEE IMPORTANT INFORMATION ON BACK
    ICSC: 0026 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

    International Chemical Safety Cards

    CHLOROANILINE, p- ICSC: 0026

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    PHYSICAL STATE; APPEARANCE:
     COLOURLESS TO YELLOW CRYSTALS.

    PHYSICAL DANGERS:

    CHEMICAL DANGERS:
     The substance decomposes on heating above 160°C and on burning producing toxic and corrosive fumes of nitrogen oxides and hydrogen chloride (see ICSC # 0163). Reacts violently with oxidants.

    OCCUPATIONAL EXPOSURE LIMITS (OELs):
     TLV not established.


    		ROUTES OF EXPOSURE:
     The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

    INHALATION RISK:
     A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C, if powdered much faster.

    EFFECTS OF SHORT-TERM EXPOSURE:
     The substance irritates the eyes, the skin and the respiratory tract. The substance may cause effects on the red blood cells , resulting in formation of methaemoglobin and hemolysis. Exposure could cause lowering of consciousness.

    EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
     Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the spleen, liver and kidneys , resulting in organ damage. Tumours have been detected in experimental animals but may not be relevant to humans (see Notes).
    PHYSICAL
    PROPERTIES
    Boiling point: 232°C
    Melting point: 69-72.5°C
    Relative density (water = 1): 1.4 (19°C)
    Solubility in water: none (see Notes)
    Vapour pressure, Pa at 20°C: 2
    Relative vapour density (air = 1): 4.4
    		 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
    Flash point: 120-123°C
    Auto-ignition temperature: 685°C
    Explosive limits, vol% in air: 2.2-?
    Octanol/water partition coefficient as log Pow: 1.8
    ENVIRONMENTAL
    DATA
    NOTES
    The substance is soluble in hot water. Depending on the degree of exposure, periodic medical examination is indicated. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
    Transport Emergency Card: TEC (R)-773
    ADDITIONAL INFORMATION


    ICSC: 0026 CHLOROANILINE, p-
    © IPCS, CEC, 1993
    IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.