International Chemical Safety Cards PENTACHLOROPHENOL ICSC: 0069 PENTACHLOROPHENOL C6Cl5OH Molecular mass: 266.4 CAS # 87-86-5 RTECS # SM6300000 ICSC # 0069 UN # 3155 EC # 604-002-00-8 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Not combustible. Liquid formulations containing organic solvents may be flammable. NO open flames, NO sparks, and NO smoking. In case of fire in the surroundings: all extinguishing agents allowed. EXPLOSION In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE PREVENT DISPERSION OF DUST! STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR! INHALATION Cough. Dizziness. Drowsiness. Headache. Laboured breathing. Sore throat. Local exhaust or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration if indicated. Refer for medical attention. SKIN MAY BE ABSORBED! Redness. Blisters (Further see Inhalation). Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention. Wear protective gloves when administering first aid. EYES Redness. Pain. Safety goggles or face shield. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Abdominal cramps. Diarrhoea. Nausea. Unconsciousness. Vomiting. Weakness (further see Inhalation). Do not eat, drink, or smoke during work. Rinse mouth. Give plenty of water to drink. Refer for medical attention. See Notes. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment (extra personal protection: P3 filter respirator for toxic particles). Provision to contain effluent from fire extinguishing. Separated from strong oxidants, food and feedstuffs. Keep in a well-ventilated room. Do not transport with food and feedstuffs. T+ symbol N symbol R: 24/25-26-36/37/38-40-50/53 S: (1/2-)22-36/37-45-52-60-61 UN Hazard Class: 6.1 UN Packing Group: II Severe marine pollutant. SEE IMPORTANT INFORMATION ON BACK ICSC: 0069 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

International Chemical Safety Cards PENTACHLOROPHENOL ICSC: 0069 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS NEEDLE-LIKE CRYSTALS OR SOLID IN VARIOUS FORMS , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating above 200°C, producing toxic fumes and toxic gases including hydrogen chloride - ICSC # 0163, dioxines, chlorinated phenols. Reacts violently with strong oxidants and water, causing fire and explosion hazard. OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV: 0.5 ppm; mg/m3 (as TWA) (skin) (ACGIH 1991-1992). MAK: class III A2; H (1993). OSHA PEL: TWA 0.5 mg/m3 skin NIOSH REL: TWA 0.5 mg/m3 skin NIOSH IDLH: 2.5 mg/m3 ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation, through the skin, and by ingestion. INHALATION RISK: EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes, the skin, and the respiratory tract. Inhalation of this substance may cause lung oedema (see Notes). The substance may cause effects on the cardiovascular system. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the central nervous system, kidneys, liver, lungs. Tumours have been detected in experimental animals but may not be relevant to humans (see Notes). PHYSICAL PROPERTIES Boiling point (decomposes): 309°C Melting point: 191°C Relative density (water = 1): 1.98 Solubility in water, g/100 ml at 20°C: 0.001 Vapour pressure, Pa at 20°C: 0.02 Relative vapour density (air = 1): 9.2 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00 Octanol/water partition coefficient as log Pow: 5.01 ENVIRONMENTAL DATA This substance may be hazardous to the environment; special attention should be given to water organisms. The substance may cause long-term effects in the aquatic environment. N O T E S The commercial product (which may be in solution) contains very toxic impurities (dioxins). Do not induce vomiting if pentachlorophenol is dissolved in organic solvents. IARC: carcinogen class IIB; CE: carcinogen category 3, R40. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered. The odour warning when the exposure limit value is exceeded is insufficient. NFPA Code: H 3; F 0; R 0; ADDITIONAL INFORMATION ICSC: 0069 PENTACHLOROPHENOL © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.