International Chemical Safety Cards

STRYCHNINE ICSC: 0197

STRYCHNINE
Strychnidin-10-one
C21H22N2O2
Molecular mass: 334.4
CAS # 57-24-9
RTECS # WL2275000
ICSC # 0197
UN # 1692
EC # 614-003-00-5
TYPES OF
HAZARD/
EXPOSURE 		ACUTE HAZARDS/
SYMPTOMS 		PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Not combustible.
NO contact with oxidizing agents.
In case of fire in the surroundings: all extinguishing agents allowed. Fire fighters should wear complete protective clothing including self-contained breathing apparatus.
EXPLOSION


EXPOSURE
AVOID ALL CONTACT!
IN ALL CASES CONSULT A DOCTOR!
  • INHALATION
    		• (see Ingestion).
    		Local exhaust or breathing protection.
    		Fresh air, rest. Artificial respiration if indicated. Refer for medical attention.
  • SKIN

    		• Protective gloves.
    		Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
  • EYES

    		• Safety goggles.
    		First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
  • INGESTION
    		• Convulsions. Stiffness of the muscles. Respiration paralysis.
    		Do not eat, drink, or smoke during work.
    		Rinse mouth. If not breathing, administer artificial respiration. Refer for medical attention. Avoid any unnecessary sensory stimulus.
    SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
    Sweep spilled substance into sealable containers. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment (extra personal protection: complete protective clothing including self-contained breathing apparatus).
    		Provision to contain effluent from fire extinguishing. Separated from strong oxidants, food and feedstuffs.
    		Do not transport with food and feedstuffs.
    T+ symbol
    R: 27/28
    S: 36/37-45
    UN Haz Class: 6.1
    UN Pack Group: I
    Marine pollutant.
    SEE IMPORTANT INFORMATION ON BACK
    ICSC: 0197 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1990 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

    International Chemical Safety Cards

    STRYCHNINE ICSC: 0197

    I
    M
    P
    O
    R
    T
    A
    N
    T

    D
    A
    T
    A
    PHYSICAL STATE; APPEARANCE:
     ODOURLESS AND COLOURLESS CRYSTALS, WITH BITTER TASTE.

    PHYSICAL DANGERS:

    CHEMICAL DANGERS:
     The substance decomposes on heating and on burning producing toxic fumes such as nitrogen oxides. Reacts with strong oxidants, causing fire and explosion hazard.

    OCCUPATIONAL EXPOSURE LIMITS:
     TLV: ppm; 0.15 mg/m3 (as TWA) (ACGIH 1992-1993).
    OSHA PEL: TWA 0.15 mg/m3
    NIOSH REL: TWA 0.15 mg/m3
    NIOSH IDLH: 3 mg/m3


    		ROUTES OF EXPOSURE:
     The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

    INHALATION RISK:
     Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

    EFFECTS OF SHORT-TERM EXPOSURE:
     The substance may cause effects on the central nervous system , resulting in convulsions, muscle contractions, respiratory failure. Exposure may result in death.


    PHYSICAL
    PROPERTIES
    Boiling point: 270°C (at 5 mmHg)°C
    Melting point (decomposes): 268-290°C
    		Relative density (water = 1): 1.36
    Solubility in water, g/100 ml: 0.014
    ENVIRONMENTAL
    DATA
         		This substance may be hazardous to the environment; special attention should be given to birds, fish, mammals.
    NOTES
    Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
    Transport Emergency Card: TEC (R)-61G09
    ADDITIONAL INFORMATION


    ICSC: 0197 STRYCHNINE
    © IPCS, CEC, 1990
    IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.