International Chemical Safety Cards ARSENIC TRICHLORIDE ICSC: 0221 ARSENIC TRICHLORIDE Arsenic III chloride Arsenous chloride AsCl3 Molecular mass: 181.2 CAS # 7784-34-1 RTECS # CG1750000 ICSC # 0221 UN # 1560 EC # 033-002-00-5 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Not combustible. NO contact with metals. In case of fire in the surroundings: all extinguishing agents allowed. Fire fighters should wear complete protective clothing including self-contained breathing apparatus. EXPLOSION Risk of fire and explosion on contact with base(s), oxidants, water and metals. Fire fighters should wear complete protective clothing including self-contained breathing apparatus. EXPOSURE AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR! INHALATION Corrosive. Cough. Laboured breathing (see Ingestion). Closed system and ventilation. Fresh air, rest. Half-upright position. Refer for medical attention. SKIN Corrosive. MAY BE ABSORBED! Redness. Pain. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention. EYES Corrosive. Pain. Severe deep burns. Face shield or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Corrosive. Abdominal pain. Burning sensation. Diarrhoea. Vomiting. Collapse. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Do NOT induce vomiting. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Consult an expert! Collect leaking and spilled liquid in sealable plastic containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent and remove to safe place. Then remove to safe place (extra personal protection: complete protective clothing including self-contained breathing apparatus). Separated from bases, oxidants, food and feedstuffs. Cool. Dry. Keep in the dark. Ventilation along the floor. Unbreakable packaging; put breakable packaging into closed unbreakable container. T symbol R: 23-25 S: 1/2-20/21-28-44 Note: A UN Hazard Class: 6.1 UN Packing Group: I Marine pollutant. UN pack method: M SEE IMPORTANT INFORMATION ON BACK ICSC: 0221 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

International Chemical Safety Cards ARSENIC TRICHLORIDE ICSC: 0221 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS, OILY, FUMING LIQUID , WITH PUNGENT ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating and under influence of light producing toxic fumes of hydrogen chloride (see ICSC # 0163) and arsenic oxides. Reacts violently with bases, strong oxidants and water, causing fire and toxic hazard. On contact with air it emits corrosive fumes of hydrogen chloride. Attacks many metals forming combustible gas (HYDROGEN - see ICSC # 0001) in presence of moisture. OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV (as As): ppm; 0.01 mg/m3 A1 (ACGIH 1993-1994). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: Corrosive. The substance is corrosive to the eyes, the skin and the respiratory tract. Inhalation of vapour may cause lung oedema (see Notes). The substance may cause effects on the cardiovascular system, central nervous system and gastrointestinal tract , resulting in severe haemorrahagic, losses of fluids and electrolytes, shock and death. Exposure may result in death. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the mucous membranes, skin, kidneys, liver and peripheral nervous system , resulting in neuropathy, pigmentation disorders, perforation of nasal septum. This substance is carcinogenic to humans. PHYSICAL PROPERTIES Boiling point: 130.2°C Melting point: -16°C Relative density (water = 1): 2.2 Solubility in water, g/100 ml: reaction Vapour pressure, kPa at 20°C: 1.17 Relative vapour density (air = 1): 6.3 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.06 ENVIRONMENTAL DATA This substance may be hazardous to the environment; special attention should be given to soil, water organisms. It is strongly advised not to let the chemical enter into the environment. NOTES The apparent melting point caused by loss of crystal water is given. Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered. Transport Emergency Card: TEC (R)-61G01 NFPA Code: H 3; F 0; R 0; ADDITIONAL INFORMATION ICSC: 0221 ARSENIC TRICHLORIDE © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.