International Chemical Safety Cards 2-BROMO-2-NITRO-1,3-PROPANEDIOL ICSC: 0415 2-BROMO-2-NITRO-1,3-PROPANEDIOL ß-Bromo-ß-nitrotrimethyleneglycol HOCH2CBr(NO2)CH2OH/C3H6O4BrN Molecular mass: 200 CAS # 52-51-7 RTECS # TY3385000 ICSC # 0415 UN # 3241 EC # 603-085-00-8 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, alcohol-resistant foam, water spray, carbon dioxide. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST! INHALATION Cough. Sore throat. Local exhaust or breathing protection. Fresh air, rest. SKIN Redness. Protective gloves. Remove contaminated clothes. Rinse skin with plenty of water or shower. EYES Redness. Stinging. Safety goggles or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place (extra personal protection: P2 filter respirator for harmful particles). Separated from food and feedstuffs and incompatible materials (see Chemical Dangers). Dry. Well closed. Keep in a well-ventilated room. Do not transport with food and feedstuffs. Xn symbol N symbol R: 21/22-37/38-41-50/53 S: (2-)26-37/39-60-61 UN Hazard Class: 6.1 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 0415 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

International Chemical Safety Cards 2-BROMO-2-NITRO-1,3-PROPANEDIOL ICSC: 0415 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: ODOURLESS WHITE CRYSTALS. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating or on burning producing toxic and corrosive fumes, including hydrogen bromide and nitrogen oxides. Reacts with some metals, amines and alkaline compounds. OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes, the skin and the respiratory tract. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact may cause skin sensitization. PHYSICAL PROPERTIES Melting point: 120-122°C Relative density (water = 1): 1.1 Solubility in water, g/100 ml at 22-25°C: 0.028 Vapour pressure, Pa at 20°C: <0.01 Octanol/water partition coefficient as log Pow: 0.18 ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. The substance may cause long-term effects in the aquatic environment. N O T E S Bronopol, Bronosol and Onyxide 500 are trade names. Transport Emergency Card: TEC (R)-61G12c NFPA Code: H1; F0; R0 ADDITIONAL INFORMATION ICSC: 0415 2-BROMO-2-NITRO-1,3-PROPANEDIOL © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.