International Chemical Safety Cards METHYL PARATHION ICSC: 0626 METHYL PARATHION O,O-Dimethyl O-4-nitrophenyl phosphorothioate p-Nitrophenylthionophosphate Phosphorothioic acid, O,O-dimethyl O-(4-nitrophenyl) ester C8H10NO5PS Molecular mass: 263.8 CAS # 298-00-0 RTECS # TG0175000 ICSC # 0626 UN # 2783 EC # 015-035-00-7 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Not combustible. Liquid formulations containing organic solvents may be flammable. See Notes. In case of fire in the surroundings: all extinguishing agents allowed. EXPLOSION Risk of fire and explosion if formulations contain flammable/explosive solvents. EXPOSURE PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! IN ALL CASES CONSULT A DOCTOR! INHALATION Sweating. Nausea. Vomiting. Dizziness. Pupillary constriction, muscle cramp, excessive salivation. Laboured breathing. Convulsions. Unconsciousness. Symptoms may be delayed (see Notes). Local exhaust or breathing protection. Fresh air, rest. Refer for medical attention. SKIN MAY BE ABSORBED! Muscle twitching. (see Inhalation). Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention. EYES Redness. Pain. Blurred vision. Pupillary constriction. face shield, or eye protection in combination with breathing protection if powder. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Nausea. Vomiting. Abdominal cramps. Diarrhoea. Pupillary constriction. Muscle cramps. Laboured breathing. Unconsciousness. Do not eat, drink, or smoke during work. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment. (extra personal protection: complete protective clothing including self-contained breathing apparatus). Separated from food and feedstuffs. Cool. Dry. Keep in the dark. Keep in a well-ventilated room. Airtight. Do not transport with food and feedstuffs. T+ symbol R: 24-28 S: (1/2-)28-36/37-45 UN Hazard Class: 6.1 UN Pack Group: I Severe marine pollutant. SEE IMPORTANT INFORMATION ON BACK ICSC: 0626 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

International Chemical Safety Cards METHYL PARATHION ICSC: 0626 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: SOLID IN VARIOUS FORMS PHYSICAL DANGERS: CHEMICAL DANGERS: Upon heating, toxic fumes are formed. OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV: 0.2 mg/m3 (as TWA) A4 (skin) (ACGIH 1997). OSHA PEL: none NIOSH REL: TWA 0.2 mg/m3 skin NIOSH IDLH: No data ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying and dust dispersion. EFFECTS OF SHORT-TERM EXPOSURE: The substance may cause effects on the nervous system , resulting in convulsion, respiratory failure, and death. Cholinesterase inhibitor. Exposure above the OEL may result in death. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the nervous system. Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms. PHYSICAL PROPERTIES Melting point: 35-38°C Relative density (water = 1): 1.4 Solubility in water, g/100 ml: 0.0055 Vapour pressure, Pa at 20°C: 0.13 Relative vapour density (air = 1): 9.1 Flash point: 46°C Octanol/water partition coefficient as log Pow: 2.68 ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment; special attention should be given to bees. N O T E S Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of acute intoxication do not become manifest until some hours have passed. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Metacide, Bladan-M, Folidol-M, Nitrox-80 are trade names. Transport Emergency Card: TEC (R)-61G41a ADDITIONAL INFORMATION ICSC: 0626 METHYL PARATHION © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.