International Chemical Safety Cards

CHLORPYRIFOS ICSC: 0851

CHLORPYRIFOS
O,O-Diethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate
C9H11Cl3NO3PS
Molecular mass: 350.6
CAS # 2921-88-2
RTECS # TF6300000
ICSC # 0851
UN # 2783
EC # 015-084-00-4
TYPES OF
HAZARD/
EXPOSURE 		ACUTE HAZARDS/
SYMPTOMS 		PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, water spray, foam, carbon dioxide.
EXPLOSION The explosion hazard will depend on the solvent used in the formulation.


EXPOSURE
STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!
IN ALL CASES CONSULT A DOCTOR!
  • INHALATION
    		• Convulsions. Dizziness. Laboured breathing. Nausea. Unconsciousness. Vomiting. Pupillary constriction, muscle cramp, excessive salivation.
    		Ventilation (not if powder), local exhaust, or breathing protection.
    		Fresh air, rest. Refer for medical attention.
  • SKIN
    		• MAY BE ABSORBED! (further see Inhalation).
    		Protective gloves. Protective clothing.
    		Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
  • EYES
    		• Blurred vision.
    		Face shield or eye protection in combination with breathing protection if powder.
    		First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
  • INGESTION
    		• Abdominal cramps. Diarrhoea. Laboured breathing. Nausea. Unconsciousness. Vomiting. Blurred vision, muscle cramps.
    		Do not eat, drink, or smoke during work.
    		Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention.
    SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
    Do NOT wash away into sewers. Sweep spilled substance into containers, carefully collect remainder, then remove to safe place. (extra personal protection: complete protective clothing including self-contained breathing apparatus).
    		Separated from food and feedstuffs, strong bases. Dry. Keep in a well-ventilated room.
    		Do not transport with food and feedstuffs.
    T symbol
    R: 23/24/25
    S: 2-13-44
    UN Haz Class: 6.1
    UN Pack Group: III
    SEE IMPORTANT INFORMATION ON BACK
    ICSC: 0851 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1990 No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and IDLH values.

    International Chemical Safety Cards

    CHLORPYRIFOS ICSC: 0851

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    PHYSICAL STATE; APPEARANCE
     COLOURLESS CRYSTALS.

    PHYSICAL DANGERS:

    CHEMICAL DANGERS:
     The substance decomposes on heating at approximately 160°C and on burning producing toxic and corrosive fumes including hydrogen chloride, nitrogen oxides, phosphorous oxides, sulfur oxides. Reacts with strong bases. Attacks copper and brass.

    OCCUPATIONAL EXPOSURE LIMITS:
     TLV: ppm; 0.2 mg/m3 (skin) (ACGIH 1991-1992).
    OSHA PEL: none
    NIOSH REL: TWA 0.2 mg/m3 ST 0.6 mg/m3 skin
    NIOSH IDLH: No data


    		ROUTES OF EXPOSURE:
     The substance can be absorbed into the body by inhalation of its aerosol, through the skin, and by ingestion.

    INHALATION RISK:
     Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered.

    EFFECTS OF SHORT-TERM EXPOSURE:
     The substance may cause effects on the nervous system , resulting in convulsions, respiratory failure. Cholinesterase inhibitor. Exposure at high levels may result in death. The effects may be delayed. Medical observation is indicated.

    EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
     Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms.
    PHYSICAL
    PROPERTIES
    Melting point: 41-43.5°C
    Relative density (water = 1): 1.398 at 43.5°C
    Solubility in water: None
    		 Vapour pressure, Pa at 25°C: 2.5 x 10-3
    Octanol/water partition coefficient as log Pow: 4.96
    ENVIRONMENTAL
    DATA
         		This substance may be hazardous to the environment; special attention should be given to crustacea and fish.
    NOTES
    Depending on the degree of exposure, periodic medical examination is indicated. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Dursban and Lorsban are trade names.
    ADDITIONAL INFORMATION


    ICSC: 0851 CHLORPYRIFOS
    © IPCS, CEC, 1990
    IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and IDLH values.